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GENITAL CANCER SCREENING Vaginal cancer may be detected during a routine pelvic examination before signs or symptoms become apparent. Doctors may also do a Pap test to look for cervical cancer, but the Pap test may detect vaginal cancer cells. Once a doctor has made a diagnosis of vaginal cancer, steps are taken to determine how far cancer has spread. Your cancer stage helps your doctor decide which treatment is right for you. FAQ Is genital cancer curable? Vaginal cancer is treatable and the treatment you have will depend on the size and type of vaginal cancer you have. What is the most common genital cancer? The most common type is vaginal squamous cell carcinoma, which begins in the thin, squamous cells that line the surface of the vagina. What is the treatment for genital cancer? The usual treatment is radiation, which uses both brachytherapy and external beam radiation therapy. Radical surgery (radical vaginectomy or pelvic exenteration) is an option for some women with stage II squamous cell carcinoma of the vagina if it is small and in the upper part of the vagina.